NASSOUR LAB
Genome Stability and Innate Immunity
Our Research
Our lab investigates how genome instability and innate immune surveillance shape cancer initiation. By integrating cell biology, biochemistry, and genetics, we define how chromosomal abnormalities trigger immune signaling and cell fate decisions, with the goal of identifying new vulnerabilities in early cancer development.
Telomeres and DNA Damage Response
We study how telomeres suppress DNA damage signaling and prevent aberrant repair at chromosome ends.
Innate Immune Sensing and Signaling
We study how innate immune pathways detect and respond to damage-associated molecular patterns (DAMPs) across molecular, cellular, and organismal scales.
Mitotic Errors and Chromosomal Instability
We study how mitotic defects and checkpoint failures drive chromosomal instability and cancer genome evolution.
We are committed to fostering a supportive, inclusive, and diverse lab environment. Our lab provides outstanding training and career development opportunities for students and postdoctoral fellows. We invite you to explore our website to learn more about our research, potential collaborations, or opportunities to join the lab.
